Can I backup just "C" drive with System Recovery 2010?

Hi, 

We run Backup System Recovery 2010 and I currently backup all the drives on our Windows 2008 SBS domain controller. I think I could restore with just the Operating System Partition (C drive), i would like your opinions/advice to see if this is a viable solution? 

Here are the details: 

• Physical Box (not virtualised)
• C drive contains Operating System Partition 
• E contains only Exchange Partition
• L contains user data like Excel, Word, PowerPoint docs ect.  It also contatains users redirected folders.
• S swap file 
• W Wsus drive 

C,E, L are all backed up everynight using symantec backup exec 2010.