Active files used by operating system skipped during backup

Hi,

I have a Backup Exec 2010 R3 installed on WIndows Server 2008 R2 in my environment. I am unable to backup active files used by operating system skipped during backup. All files are able to backup except for this 'httpd.exe' which is used by apache software running. I have selected Advance Open File Option and used Microsoft shadow copy as the VSS option but it is not working.

Anyone encounter this before?

Regards,
Chiew Sheng